Liquid Ocelot

During the Shadow Moses Incident. Ocelot(Shiro) managed to lose his arm(Like he does in Legendary Defender) and instead of opting for a Cybernetic one, he had a arm transplant involving Liquid Snake(Lotor). This resulted in a disturbing Shiro/Lotor Hybrid, also known as Shotor.

During the eventsof MGQ4, Liquid instigates an event known as "Guns Of The Patriots". And Snake, realizing Shiro had nothing left in him, beat him to death onboard Outer Haven.