Actors

Bex Taylor Klaus as Meryl Holt/Pidge

Jeremy Shada as Lance

Debi Mae West as Big Mama/Pidge.

David Hayter as Solid Snake/Keith/Big Boss.

Jeremy Shada and Norman Reedus as Lance/Quintessence Snake.

Rhys Darby as Coran/Major Zero.

AJ Locascio as Liquid Snake/Lotor.

Neil Kaplan as Solidus Snake/Zarkon.

Josh Keaton as Young Ocelot/Shiro.

Troy Baker as Middle Aged Ocelot/Shiro.

Patric Zimmerman as Ocelot/Shiro.

Rob Paulsen as Gray Fox.

Tyler Labine as Johnny "Hunk" Sasaki.

Michael Gough(No relation to Michael Guinn) as 1960s Johnny Sasaki.

Christopher Randolph as Matthew "Otacon" Holt/Huey Holt.

Paul Eiding as Roy Samuel Campbell.

Quinton Flynn as Raiden/Raikov.

Guest Appearances

Stephen Merchant as 1984 Fellow Otaku Nerd of Huey, who stares at the screen watching 1984 Voltron.

Idris Elba.

Matthew Mercer as Journalist Albert Genelle(The first time a Namco Character from Ace Combat crosses into the Metal Gear Universe, just don't expect him to say "It's High Noon").

Jamie Gray Hyder(she makes a quip that references both her role in Voltron and Infinite Warfare).

Neil Ross as Volgin and 1984 Pidge(Why am I a man? Big Mama says at the TV).

Yuri Lowenthal.